Nothing plugged in. Still read the label warnings and tell your doctor and pharmacist about every supplement you take.
- Diabetes medicine or insulinAlpha lipoic acid · Magnesium glycinate · Coenzyme Q10
Alpha lipoic acid can lower blood sugar and, MSK says, may have a synergistic effect with diabetes medicines, so low blood sugar is the concern. Magnesium may raise the absorption of sulfonylurea drugs. NCI says coenzyme Q10 may change how the body uses insulin. Know the signs of low blood sugar: shaky, sweaty, dizzy, confused, a fast heartbeat. Ask your doctor or pharmacist first and keep taking your prescribed medicine. (MSK, Alpha-lipoic acid) (MSK, Magnesium) (NCI, Coenzyme Q10) (NIDDK, Low blood glucose)
- Blood thinner (warfarin, clopidogrel, apixaban, rivaroxaban) or aspirinTurmeric extract · Coenzyme Q10 · L-carnitine · Magnesium glycinate
MSK says turmeric may raise bleeding risk and L-carnitine may add to warfarin. Mayo Clinic says coenzyme Q10 might make warfarin work less well, which could raise the risk of a clot. MSK adds that magnesium may raise the absorption of anticoagulants. These pull in different directions, so a clinician should check your exact medicine. (MSK, Turmeric) (MSK, Carnitine) (Mayo Clinic, Coenzyme Q10) (MSK, Magnesium)
- Blood pressure medicineMagnesium glycinate · Butcher's broom root extract · Coenzyme Q10
MSK says magnesium may add to the blood-pressure-lowering effect of calcium channel blockers. WebMD lists a medicine for high blood pressure among those to discuss before butcher's broom. NCI says blood pressure medicines may decrease the effects of coenzyme Q10. Ask your pharmacist. (MSK, Magnesium) (WebMD, Butcher's broom) (NCI, Coenzyme Q10)
- Enlarged prostate medicine or a decongestant (pseudoephedrine)Butcher's broom root extract
WebMD lists a medicine for an enlarged prostate and pseudoephedrine among the medicines to discuss before butcher's broom, and Drugs.com says interactions with alpha-adrenergic agents are theoretically possible. The interactions are not fully understood, so ask your pharmacist. (WebMD, Butcher's broom) (Drugs.com, Butcher's broom)
- Antibiotics (tetracyclines, fluoroquinolones, nitrofurantoin, pivampicillin)Magnesium glycinate · L-carnitine
NIH says tetracycline and quinolone antibiotics should be taken at least 2 hours before or 4 to 6 hours after a magnesium supplement. NIH also lists pivalate-conjugated antibiotics such as pivampicillin as interacting with carnitine. Ask your pharmacist how to space them. (NIH ODS, Magnesium) (NIH ODS, Carnitine)
- Thyroid hormone medicine (levothyroxine)L-carnitine
In a 2001 randomized trial, 2 to 4 g a day of L-carnitine acted against thyroid hormone in women taking levothyroxine. The label prints no carnitine amount, so we cannot say if a capsule is close to that, but ask your pharmacist if you take thyroid medicine. (Benvenga 2001, Carnitine and thyroid hormone)
- Seizure medicine (valproic acid, phenobarbital, phenytoin, carbamazepine)L-carnitine
NIH lists these seizure medicines as interacting with carnitine. Ask your pharmacist or neurologist. (NIH ODS, Carnitine)
- Water pills, long-term acid reducers (PPIs) or bisphosphonatesMagnesium glycinate
NIH says loop and thiazide diuretics and long-term proton pump inhibitor use can lower magnesium, and bisphosphonates should be spaced 2 hours from magnesium. Ask your pharmacist. (NIH ODS, Magnesium)
- Chemotherapy or radiationAlpha lipoic acid · Coenzyme Q10 · Turmeric extract · L-carnitine
MSK says alpha lipoic acid and coenzyme Q10 may reduce the effect of chemotherapy and radiation, and that turmeric may lessen some chemotherapy medicines. MSK adds that acetyl-L-carnitine can increase nerve pain caused by chemotherapy. Ask your oncology team before any supplement. (MSK, Alpha-lipoic acid) (MSK, Coenzyme Q10) (MSK, Turmeric) (MSK, Carnitine)
- Kidney or liver problemsMagnesium glycinate · Turmeric extract · Butcher's broom root extract
MSK says not to take magnesium supplements with kidney failure. NCCIH says highly bioavailable curcumin may harm the liver. WebMD says to tell a provider about kidney or liver problems before butcher's broom. (MSK, Magnesium) (NCCIH, Turmeric) (WebMD, Butcher's broom)
- Pregnant, trying to conceive or breastfeedingCoenzyme Q10 · Butcher's broom root extract
Mayo Clinic says not to use coenzyme Q10 while pregnant or breastfeeding without a professional's approval. WebMD says it is not known whether butcher's broom affects pregnancy, and Drugs.com says to avoid it. Ask your clinician. (Mayo Clinic, Coenzyme Q10) (WebMD, Butcher's broom) (Drugs.com, Butcher's broom)
- Surgery or dental work in the next two weeksApplies to every supplement
NCCIH says some supplements may increase bleeding or affect anesthesia, so tell your surgeon about every supplement well before surgery. (NCCIH, Using supplements wisely)